IMR Press / CEOG / Volume 46 / Issue 1 / DOI: 10.12891/ceog4196.2019
Open Access Original Research
Perinatal outcome of prolonged preterm premature rupture of membranes near the limit of fetal viability
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1 Perinatal Center for Maternity and Neonate, Yokohama City University Medical Center, Yokohama, Japan
2 Department of Biostatistics and Epidemiology, Yokohama City University Graduate School of Medicine and University Medical Center, Yokohama, Japan
3 Department of Obstetrics and Gynecology, Yokohama City University Hospital, Yokohama, Japan
Clin. Exp. Obstet. Gynecol. 2019 , 46(1), 16–20; https://doi.org/10.12891/ceog4196.2019
Published: 10 February 2019
Abstract

Purpose of investigation: The purpose of the present study is to evaluate the perinatal outcome of expectant management for prolonged preterm premature rupture of membranes (PPROM) near the limit of fetal viability. Materials and Methods: Pregnant women who delivered babies between January 2000 and March 2015 and had a history of PPROM at 22-23 weeks of gestation with a latency of one week or longer were included in the PPROM cohort. The control cohort included women who delivered babies within 24 hours after PPROM during the same period. Perinatal outcomes were compared between the two cohorts. Results: No differences were observed between the two cohorts in terms of survival to discharge from the NICU (p = 0.43) and respiratory complication at one year of corrected AGE (p = 1.00). Conclusions: Prolonged PPROM did not affect the rate of survival discharge from NICU and respiratory complication at one year of corrected age.

Keywords
Premature rupture of membranes
Expectant management
Perinatal outcome
Fetal viability
Respiratory complication
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