IMR Press / CEOG / Volume 46 / Issue 5 / DOI: 10.12891/ceog4808.2019
Open Access Case Report
Pulmonary lymphangioleiomyomatosis as an uncommon cause of recurrent early pregnancy loss
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1 Department of Obstetrics and Gynecology, School of Medicine, Karadeniz Technical University, Trabzon, Turkey
Clin. Exp. Obstet. Gynecol. 2019 , 46(5), 831–832; https://doi.org/10.12891/ceog4808.2019
Published: 10 October 2019
Abstract

Pulmonary lymphangioleimyomatosis (LAM) is a rare disorder characterized by hamartomatous proliferation of smooth muscle within lung parenchyma. LAM occurs only in women and exacerbates with menstruation, estrogen use, and taking oral contraceptives. The effect of pulmonary LAM on recurrent pregnancy loss has not been reported previously. A 28-years-old (gravida 2 parity 0 abortion 2) woman was admitted to the gynecology outpatient clinic because of habitual abortion. The patient had a history of early (one 8-week and another 6-week) pregnancy losses. CT scan showed widespread and varied dimension thin edge cystic lesions extending to about 1 cm in diameter of the largest size observed in all segments of both lungs. All other recurrent pregnancy loss tests were within normal limits, except pulmonary LAM findings on CT scan. Clinicians should keep in mind the diagnosis of pulmonary LAM, in cases with progressive dyspnea (especially in luteal phase of menstruation) and recurrent pregnancy losses.

Keywords
Fibronectin
Habitual abortion
Invasion
Pulmonary lymphangioleiomyomatosis
Figures
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