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A case report supporting the concept that a role for the anti-Müllerian hormone (AMH) in normal folliculogenesis is to diminish the biological activity of follicle stimulating hormone (FSH)
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1
Cooper Medical School of Rowan University, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, United States
2
Cooper Institute for Reproductive Hormonal Disorders, P.C., Mt. Laurel, NJ, United States
*Correspondence: laurie@ccivf.com (JEROME H. CHECK)
Clin. Exp. Obstet. Gynecol. 2020, 47(4), 620–621;
https://doi.org/10.31083/j.ceog.2020.04.5178
Submitted: 12 March 2019 | Accepted: 2 May 2019 | Published: 15 August 2020
Copyright: © 2020 Check et al. Published by IMR Press.
This is an open access article under the CC BY 4.0 license
http://creativecommons.org/licenses/by/4.0/.
Abstract
Purpose: To describe a case where a woman was ovulating with regular menses despite very low sera follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels. Case Report: Serum anti-Müllerian (AMH) was obtained because the woman was to be an egg donor for her identical twin sister. This 28-year-old woman responded fairly well to controlled ovarian hyperstimulation producing ten metaphase II eggs and eight fertilized and were cryopreserved on day 3. Her serum AMH level was subnormal at 0.6 ng/mL. Conclusions: This case suggests that FSH may be more biologically active in the presence of low AMH.
Keywords
Decreased oocyte reserve
Anti-Müllerian hormone
Gonadotropin deficiency
FSH induced aromatase enzyme