IMR Press / EJGO / Volume 41 / Issue 3 / DOI: 10.31083/j.ejgo.2020.03.5039
Open Access Review
Endometrial stromal nodule: report of 8 cases and literature review
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1 Laboratory of Gynecologic Oncology, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
2 Department of Gynecology, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
3 Department of Radiology, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Eur. J. Gynaecol. Oncol. 2020 , 41(3), 332–338; https://doi.org/10.31083/j.ejgo.2020.03.5039
Submitted: 11 October 2018 | Accepted: 25 February 2019 | Published: 15 June 2020
Abstract

Endometrial stromal nodule (ESN) is a rare and benign tumor of endometrial stromal origin that accounts for less than 10% of uterine mesenchymal neoplasms. It is difficult and yet essential to preoperatively differentiate endometrial stromal nodule from other types of mesenchymal malignancies, considering that the therapeutic options and clinical outcomes are totally different. To better guide clinical practice, the authors herein report eight cases diagnosed with endometrial stromal nodule and analyze the clinical and pathological characteristics, and also perform a literature review of endometrial stromal nodule. Authors of the present study conclude that conservative surgery with fertility-sparing is feasible for a suspected diagnosis of endometrial stromal nodule when ultrasonography suggests hypoechoic masses with cystic degeneration or liquefaction and magnetic resonance imaging showed a well circumscribed mass exhibiting isointensity on T1-weighted images, hyperintensity on T2-weighted images, and hyperintensity on diffusion-weighted images.

Keywords
Endometrial stromal nodule
Literature review
Magnetic resonance imaging
Fertility sparing
Treatment
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