IMR Press / EJGO / Volume 41 / Issue 4 / DOI: 10.31083/j.ejgo.2020.04.3936
Open Access Case Report
Collision tumour of endometrial stromal sarcoma, uterine tumour resembling ovarian sex-cord tumour, and leiomyoma
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1 Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Oita, Japan
2 Division of Obstetrics and Gynecology, Support System for Community Medicine, Faculty of Medicine, Oita University, Oita, Japan
3 Department of Obstetrics and Gynecology, Nakatsu Municipal Hospital, Oita, Japan
4 Department of Diagnostic Pathology, Faculty of Medicine, Oita University, Oita, Japan
Eur. J. Gynaecol. Oncol. 2020 , 41(4), 634–637; https://doi.org/10.31083/j.ejgo.2020.04.3936
Submitted: 30 July 2016 | Accepted: 24 October 2019 | Published: 15 August 2020
Abstract

Purpose of investigation: Endometrial stromal (ES) tumours may show different types of differentiation including smooth muscle and sex-cord like elements. A common problem is the differential diagnosis of ES tumour variants from other tumours that have smooth muscle or sex cord-like elements. We report a case of collision tumour that was composed of a low-grade endometrial stromal sarcoma (ESS) with sex-cord like differentiation, a uterine tumour resembling ovarian sex-cord tumour (UTROSCT), and a leiomyoma. Result: The patient was a 63-year-old multiparous woman who was referred to us with the complaint of recurrent abnormal uterine bleeding. Magnetic resonance imaging demonstrated a 3.4-cm-dia. solid tumour in her uterine cavity. We performed an abdominal total hysterectomy and a bilateral salpingo-oophorectomy. On gross and microscopic examination, the tumour consisted of a CD10-positive low-grade ESS, a CD10-negative UTROSCT, and a leiomyoma. Conclusion: ESS should be distinguished from UTROSCT and leiomyoma because of its malignant potential.

Keywords
Endometrial stromal sarcoma
Leiomyoma
Sex-cord differentiation
Uterine neoplasm
Uterine tumour resembling ovarian sex-cord tumour
Figures
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