Volume 29 Issue 3 2024

• Open Access Original Research

  Deciphering a Prognostic Signature Based on Soluble Mediators Defines the Immune Landscape and Predicts Prognosis in HNSCC

  Hao Chi, Gaoge Peng, Guobin Song, Jinhao Zhang, ... Guanhu Yang

  Front. Biosci. (Landmark Ed) 2024, 29(3), 130; https://doi.org/10.31083/j.fbl2903130

  Abstract Full Text PDF(11.51MB)

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• Open Access Original Research

  A Novel Cholesterol Metabolism-Related lncRNA Signature Predicts the Prognosis of Patients with Hepatocellular Carcinoma and Their Response to Immunotherapy

  Hui Lei, Tao Xiang, Hua Zhu, Xinyao Hu

  Front. Biosci. (Landmark Ed) 2024, 29(3), 129; https://doi.org/10.31083/j.fbl2903129

  (This article belongs to the Special Issue The Impact of Metabolic Gene Signature with Respect to Tumor Prognosis, Microenvironment, and Immunotherapy)

  Abstract Full Text PDF(8.57MB)

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• Open Access Original Research

  Chronic Viral Infection Compromises the Quality of Circulating Mucosal–Associated Invariant T Cells and Follicular T Helper Cells via Expression of Inhibitory Receptors

  Jaisheela Vimali, Yean K. Yong, Amudhan Murugesan, Hong Y. Tan, ... Esaki M. Shankar

  Front. Biosci. (Landmark Ed) 2024, 29(3), 128; https://doi.org/10.31083/j.fbl2903128

  Abstract Full Text PDF(5.07MB)

  48

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  143

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• Open Access Original Research

  Histopathological and Immunohistochemical Mechanisms of Bone Marrow-Derived Mesenchymal Stem Cells in Reversion of Gastric Precancerous Lesions

  Qian-Qian Chen, Cong Wang, Wei-Hua Wang, Yuan Gong, Hai-Xu Chen

  Front. Biosci. (Landmark Ed) 2024, 29(3), 127; https://doi.org/10.31083/j.fbl2903127

  Abstract Full Text PDF(14.31MB)

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• Open Access Review

  Epigenetic Modifications in Genome Help Remembering the Stress Tolerance Strategy Adopted by the Plant

  Suresh Kumar, Trilochan Mohapatra

  Front. Biosci. (Landmark Ed) 2024, 29(3), 126; https://doi.org/10.31083/j.fbl2903126

  Abstract Full Text PDF(11.09MB)

  181

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  363

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• Open Access Original Research

  Identification of Down-Expressed CRNN Associated with Cancer Progression and Poor Prognosis in Laryngeal Squamous Cell Carcinoma

  Feilong Hong, Xuemei Wan, Yundan Bai

  Front. Biosci. (Landmark Ed) 2024, 29(3), 125; https://doi.org/10.31083/j.fbl2903125

  Abstract Full Text PDF(25.78MB)

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• Open Access Original Research

  Sexual Dimorphism in the Physiopathology and Immune Response during Acute Toxocara canis Infection

  Víctor Hugo Del Río-Araiza, Yazmín Alcalá-Canto, Claudia Angélica Garay-Canales, Karen Elizabeth Nava-Castro, Jorge Morales-Montor

  Front. Biosci. (Landmark Ed) 2024, 29(3), 124; https://doi.org/10.31083/j.fbl2903124

  Abstract Full Text PDF(1.10MB)

  26

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  119

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• Open Access Original Research

  Exploring the Role of DNA Methylation Located in Cuproptosis-Related Genes: Implications for Prognosis and Immune Landscape in Hepatocellular Carcinoma

  Rui Zhu, Xue Wang, Fenyong Sun, Liucun Zhu, Wenna Guo

  Front. Biosci. (Landmark Ed) 2024, 29(3), 123; https://doi.org/10.31083/j.fbl2903123

  Abstract Full Text PDF(8.84MB)

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• Open Access Editorial

  Molecular Signalling Pathways Regulating Cell Survival, Death and Differentiation

  Rebecca Piccarducci, Simona Daniele

  Front. Biosci. (Landmark Ed) 2024, 29(3), 122; https://doi.org/10.31083/j.fbl2903122

  (This article belongs to the Special Issue Molecular Signaling Pathways Regulating Cell Survival, Death and Differentiation)

  Abstract Full Text PDF(180.79KB)

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• Open Access Original Research

  An Integrated Machine Learning Framework Identifies Prognostic Gene Pair Biomarkers Associated with Programmed Cell Death Modalities in Clear Cell Renal Cell Carcinoma

  Bohong Chen, Mingguo Zhou, Li Guo, Haoxiang Huang, ... Wei Chen

  Front. Biosci. (Landmark Ed) 2024, 29(3), 121; https://doi.org/10.31083/j.fbl2903121

  Abstract Full Text PDF(20.49MB)

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  115

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• Open Access Original Research

  METTL3 Promotes Osteosarcoma Metastasis via an m6A-dependent Epigenetic Activity of CBX4

  Xi-song Huo, Dan Lu, Da-gui Chen, Min Ye, ... Fu-sheng Shang

  Front. Biosci. (Landmark Ed) 2024, 29(3), 120; https://doi.org/10.31083/j.fbl2903120

  Abstract Full Text PDF(30.31MB)

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• Open Access Original Research

  EIF2Ss, a Novel c-Myc-Correlated Gene Family, is Associated with Poor Prognosis and Immune Infiltration in Pancreatic Adenocarcinoma

  Zhangqi Cao, Yanhua Jing, Chienshan Cheng, Fengjiao Wang, ... Zhen Chen

  Front. Biosci. (Landmark Ed) 2024, 29(3), 119; https://doi.org/10.31083/j.fbl2903119

  Abstract Full Text PDF(5.58MB)

  16

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  66

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• Open Access Review

  Locus Coeruleus-Norepinephrine System: Spheres of Influence and Contribution to the Development of Neurodegenerative Diseases

  Vladimir Nikolaevich Nikolenko, Irina Dmitriyevna Borminskaya, Arina Timofeevna Nikitina, Maria Sergeevna Golyshkina, ... Marine Valikovna Oganesyan

  Front. Biosci. (Landmark Ed) 2024, 29(3), 118; https://doi.org/10.31083/j.fbl2903118

  (This article belongs to the Special Issue New Therapeutic Avenues in Neurodegenerative Diseases: What to Expect in the Future)

  Abstract Full Text PDF(2.74MB)

  63

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  269

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• Open Access Original Research

  YTHDF1 Promotes Proliferation and Inhibits Apoptosis of Gastric Cancer Cells via Upregulating TCF7 mRNA Translation

  Yuqiang Li, Xiong Guo, Xiaolong Liang, Ziwei Wang

  Front. Biosci. (Landmark Ed) 2024, 29(3), 117; https://doi.org/10.31083/j.fbl2903117

  Abstract Full Text PDF(11.51MB)

  22

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  86

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• Open Access Short Communication

  Host Cell-dependent Modulatory Role of Ras Homolog Enriched in Brain-Like-1 (RhebL1) Protein in Influenza A/NWS/33 Virus-infected Mammalian Cells

  Mirko Buttrini, Flora De Conto

  Front. Biosci. (Landmark Ed) 2024, 29(3), 116; https://doi.org/10.31083/j.fbl2903116

  (This article belongs to the Special Issue Research on Influenza Viruses)

  Abstract Full Text PDF(1.78MB)

  21

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  87

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• Open Access Original Research

  Interferon Regulatory Factor 4 (IRF4) Plays a Key Role in Osteoblast Differentiation of Postmenopausal Osteoporosis

  Xuan Wu, Cuicui Yang, Xiangxu Chen, Zhengming Shan, Xiaotao Wu

  Front. Biosci. (Landmark Ed) 2024, 29(3), 115; https://doi.org/10.31083/j.fbl2903115

  Abstract Full Text PDF(3.28MB)

  21

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  59

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• Open Access Review

  The Role of Human Pluripotent Stem Cells in Amyotrophic Lateral Sclerosis: From Biological Mechanism to Practical Implications

  Laura Ceccarelli, Lorenzo Verriello, Giada Pauletto, Mariarosaria Valente, ... Tamara Ius

  Front. Biosci. (Landmark Ed) 2024, 29(3), 114; https://doi.org/10.31083/j.fbl2903114

  Abstract Full Text PDF(919.62KB)

  41

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  96

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• Open Access Review

  Is Osteoarthritis a Vascular Disease?

  Jon Olansen, Jonathan P. Dyke, Roy K. Aaron

  Front. Biosci. (Landmark Ed) 2024, 29(3), 113; https://doi.org/10.31083/j.fbl2903113

  Abstract Full Text PDF(7.01MB)

  40

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  111

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• Open Access Original Research

  Antimicrobial Resistance and the Genomic Epidemiology of Multidrug-Resistant Salmonella enterica serovar Enteritidis ST11 in China

  Jie Liu, Yue Hou, Linna Zhao, Gang Chen, ... Chengbin Wang

  Front. Biosci. (Landmark Ed) 2024, 29(3), 112; https://doi.org/10.31083/j.fbl2903112

  Abstract Full Text PDF(3.48MB)

  32

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  82

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• Open Access Original Research

  Antibacterial Properties of Bacterial Endophytes Isolated from the Medicinal Plant Origanum heracleoticum L.

  Giulia Semenzato, Alberto Bernacchi, Sara Amata, Angela Bechini, ... Renato Fani

  Front. Biosci. (Landmark Ed) 2024, 29(3), 111; https://doi.org/10.31083/j.fbl2903111

  Abstract Full Text PDF(3.40MB)

  46

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  76

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• Open Access Original Research

  Electroosmotic and Gyrotactic Microorganisms Effects on MHD Al₂O₃-Cu/Blood Hybrid Nanofluid Flow through Multi-Stenosed Bifurcated Artery

  Umesh Khanduri, Bhupendra Kumar Sharma, Bandar Almohsen, Muhammad Mubashir Bhatti

  Front. Biosci. (Landmark Ed) 2024, 29(3), 110; https://doi.org/10.31083/j.fbl2903110

  Abstract Full Text PDF(11.20MB)

  33

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  53

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• Open Access Original Research

  The Protective Effects of Ecdysterone on Cognitive Impairment through Regulating Akt/GSK-3β/Nrf2 Signaling Pathway and Oxidative Stress in Cognitive Mice Model and Aβ-Induced Cell Neurotoxicity

  Haihui Xing, Guohua Chen, Faisal Raza, Hajra Zafar, ... Dan Chen

  Front. Biosci. (Landmark Ed) 2024, 29(3), 109; https://doi.org/10.31083/j.fbl2903109

  Abstract Full Text PDF(19.75MB)

  28

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  98

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• Open Access Original Research

  Chitosan Membranes Stabilized with Varying Acyl Lengths Release Cis-2-Decenoic Acid and Bupivacaine at Controlled Rates and Inhibit Pathogenic Biofilm

  Landon Reed Choi, Zoe Harrison, Emily C. Montgomery, Joshua R. Bush, ... Jessica Amber Jennings

  Front. Biosci. (Landmark Ed) 2024, 29(3), 108; https://doi.org/10.31083/j.fbl2903108

  Abstract Full Text PDF(30.53MB)

  15

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  50

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• Open Access Original Research

  From Sleep Deprivation to Severe COVID-19: A Comprehensive Analysis of Shared Differentially Expressed Genes and Potential Diagnostic Biomarkers

  Jing Peng, Xiaocheng Zhu, Wuping Zhuang, Hui Luo, E Wang

  Front. Biosci. (Landmark Ed) 2024, 29(3), 107; https://doi.org/10.31083/j.fbl2903107

  Abstract Full Text PDF(22.09MB)

  19

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  55

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• Open Access Original Research

  Cisplatin Disrupts Proteasome Bounce-Back Effect through Suppressing ZEB1/Nfe2l1 in Cholangiocarcinoma

  Yuancai Xiang, Man Jia, Yuan Gao, Fang Yang, ... Hongming Miao

  Front. Biosci. (Landmark Ed) 2024, 29(3), 106; https://doi.org/10.31083/j.fbl2903106

  Abstract Full Text PDF(3.12MB)

  33

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  95

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• Open Access Review

  Unveiling the Role of Hydrolytic Enzymes from Soil Biocontrol Bacteria in Sustainable Phytopathogen Management

  Roohallah Saberi Riseh, Masoumeh Vatankhah, Mohadeseh Hassanisaadi, Essaid Ait Barka

  Front. Biosci. (Landmark Ed) 2024, 29(3), 105; https://doi.org/10.31083/j.fbl2903105

  (This article belongs to the Special Issue Endophytic Bacteria: Microbial Ecology, Genomic Analysis and Biotechnological Applications)

  Abstract Full Text PDF(9.23MB)

  68

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  78

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• Open Access Original Research

  NOP14 as a Potential Predictor of Adult-Type Diffuse Glioma Prognosis and Immunotherapy, is Related to Cell Migration, Proliferation, and CD8⁺T Cell Infiltration

  Qiu-si Tian, Jing Cheng, Zhi-jun Bao

  Front. Biosci. (Landmark Ed) 2024, 29(3), 104; https://doi.org/10.31083/j.fbl2903104

  Abstract Full Text PDF(5.69MB)

  15

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  64

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• Open Access Review

  Genetic Contributions to Recovery following Brain Trauma: A Narrative Review

  Deepak Lakshmipathy, Shreya Rangarajan, Ariana Barreau, Jeffrey Lu, ... Brandon Lucke-Wold

  Front. Biosci. (Landmark Ed) 2024, 29(3), 103; https://doi.org/10.31083/j.fbl2903103

  Abstract Full Text PDF(1.22MB)

  24

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  114

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• Open Access Review

  Impact of Toll-Like Receptors (TLRs) and TLR Signaling Proteins in Trigeminal Ganglia Impairing Herpes Simplex Virus 1 (HSV-1) Progression to Encephalitis: Insights from Mouse Models

  Marco Antônio Campos, Guilherme de Pádua Zolini, Erna Geessien Kroon

  Front. Biosci. (Landmark Ed) 2024, 29(3), 102; https://doi.org/10.31083/j.fbl2903102

  (This article belongs to the Special Issue Toll-Like Receptors in Various Pathologies)

  Abstract Full Text PDF(2.13MB)

  32

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  114

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• Open Access Review

  Molecular Classification and Pathogenesis of Pancreatic Adenocarcinoma and Targeted Therapies: A Review

  Samantha M. Ruff, Timothy M. Pawlik

  Front. Biosci. (Landmark Ed) 2024, 29(3), 101; https://doi.org/10.31083/j.fbl2903101

  Abstract Full Text PDF(1.24MB)

  50

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  150

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• Open Access Original Research

  Single-Cell Transcriptome Analysis of Small Cell Neuroendocrine Carcinoma of the Endometrium Reveals ISL1 as a Potential Biomarker for Diagnosis and Treatment

  Cheng Zhong, Yu-e Guo, Qianlan Yang, Yunfeng Song, ... Xiaoping Wan

  Front. Biosci. (Landmark Ed) 2024, 29(3), 100; https://doi.org/10.31083/j.fbl2903100

  Abstract Full Text PDF(8.83MB)

  36

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  89

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• Open Access Review

  The Molecular Mechanisms behind Advanced Breast Cancer Metabolism: Warburg Effect, OXPHOS, and Calcium

  Erna Mitaishvili, Hanna Feinsod, Zachary David, Jessica Shpigel, ... Columba de la Parra

  Front. Biosci. (Landmark Ed) 2024, 29(3), 99; https://doi.org/10.31083/j.fbl2903099

  Abstract Full Text PDF(1.77MB)

  78

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  377

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• Open Access Original Research

  Prognostic Model Associated with Necroptosis in Colorectal Cancer based on Transcriptomic Analysis and Experimental Validation

  Yuying Huang, Licheng Li, Zhongmin Kang, Huali Luo, ... Mengxing Li

  Front. Biosci. (Landmark Ed) 2024, 29(3), 98; https://doi.org/10.31083/j.fbl2903098

  Abstract Full Text PDF(14.00MB)

  21

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  106

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• Open Access Original Research

  The Prognostic and Immune Significance of BZW2 in Pan-Cancer and its Relationship with Proliferation and Apoptosis of Cervical Cancer

  Chaolin Li, Qin Li, Li Li, Siyu Sun, Xun Lei

  Front. Biosci. (Landmark Ed) 2024, 29(3), 97; https://doi.org/10.31083/j.fbl2903097

  Abstract Full Text PDF(21.08MB)

  17

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• Open Access Original Research

  Conditioned Media from Deer Antler Stem Cells Effectively Alleviate Type 1 Diabetes Mellitus Possibly via Inhibiting the NF-κB Signaling Pathway

  Dongxu Wang, Jing Ren, Jiping Li, Xiuying Li, ... Guokun Zhang

  Front. Biosci. (Landmark Ed) 2024, 29(3), 96; https://doi.org/10.31083/j.fbl2903096

  Abstract Full Text PDF(6.10MB)

  19

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  82

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• Open Access Original Research

  Melatonin Alleviates BPA-Induced Testicular Apoptosis and Endoplasmic Reticulum Stress

  Qi Qi, Lei Feng, Jingjing Liu, Da Xu, ... Xiaoyan Pan

  Front. Biosci. (Landmark Ed) 2024, 29(3), 95; https://doi.org/10.31083/j.fbl2903095

  Abstract Full Text PDF(17.05MB)

  29

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• Open Access Review

  Astrocytes in Spinal Cord Injury: Current Opportunities and Prospects for Directional Polarization

  Aizilya Bilalova, Olga Tutova, Yana Mukhamedshina, Albert Rizvanov

  Front. Biosci. (Landmark Ed) 2024, 29(3), 94; https://doi.org/10.31083/j.fbl2903094

  Abstract Full Text PDF(1.89MB)

  52

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  110

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• Open Access Original Research

  The Mechanism of Polygonum Hydropiper L-Coptis Chinensis in the Treatment of Ulcerative Colitis Based on Network Pharmacology and Experimental Validation

  Feifei Zhu, Yunyun Zhi, Yonghui Li, Haiyan Niu, Shouzhong Ren

  Front. Biosci. (Landmark Ed) 2024, 29(3), 93; https://doi.org/10.31083/j.fbl2903093

  Abstract Full Text PDF(9.56MB)

  31

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  72

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• Open Access Review

  Phosphoglycerate Kinase 1: An Effective Therapeutic Target in Cancer

  Ailin Qiu, Xiaosha Wen, Qingshuang Zou, Lei Yin, ... Zifen Guo

  Front. Biosci. (Landmark Ed) 2024, 29(3), 92; https://doi.org/10.31083/j.fbl2903092

  Abstract Full Text PDF(7.06MB)

  34

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• Open Access Original Research

  Bioinformatics-Based Screening of Key LncRNAs for Modulating the Transcriptome Associated with Glaucoma in Human Trabecular Meshwork Cells

  Junhong Guo, Yunfei Wu, Yue Sun, Dong Chen, ... Jiantao Wang

  Front. Biosci. (Landmark Ed) 2024, 29(3), 91; https://doi.org/10.31083/j.fbl2903091

  Abstract Full Text PDF(3.05MB)

  34

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  116

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