Cancer; Epithelial to mesenchymal transition; Signal transduction; TGF-beta/bmp/smad signaling pathway; Wnt signaling; notch signaling; TNF signaling; Immunology; CAR-T cell therapy; Immune checkpoint inhibitors; Immuno-oncology; CRISPR-Cas9; Inflammation; Membrane proteins; Protein translation; Receptors and membrane biology; Ubiquitination; Sumoylation; Translational research; Tumour immunology; Biomarkers