We evaluated the performance of arterial spin-labeled perfusion imaging and
diffusion-weighted imaging in diagnosing full-term neonatal hypoxic-ischemic
encephalopathy. Arterial spin-labeled, diffusion-weighted imaging and
conventional magnetic resonance imaging (T1-weighted imaging, T2-weighted imaging
and T2 fluid-attenuated inversion recovery) were performed in 23 full-term
neonates with hypoxic-ischemic encephalopathy group 10 normal neonates (Control
group). The cerebral blood flow and the apparent diffusion coefficient were
measured in the bilateral basal ganglia, thalamus and frontal white matter. The
effect of neonatal age on the CBF and apparent diffusion coefficient values were
further investigated after dividing the 23 ischemic encephalopathy cases into
three subgroups (1–3 days, 4–7 days, and 8–15 days). The cerebral blood flow
values in the thalamus and lenticular nucleus were significantly higher. The
apparent diffusion coefficient values in the thalamus, frontal white matter and
lenticular nucleus head were significantly lower in the hypoxic-ischemic
encephalopathy group than those in the Control group (p
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Diagnostic performance of arterial spin-labeled perfusion imaging and diffusion-weighted imaging in full-term neonatal hypoxic-ischemic encephalopathy
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1
Department of Radiology, The Second Hospital of Shandong University, 250033 Jinan, Shandong, China
2
Department of Radiology, Qilu Hospital of Shandong University, 250012 Jinan, Shandong, China
3
Department of Radiology, Rizhao People’s Hospital, 276800 Rizhao, Shandong, China
4
Department of Pediatrics, Qilu Hospital of Shandong University, 250012 Jinan, Shandong, China
*Correspondence: 2019120135@mail.sdu.edu.cn; qlradiology@163.com (Qing Wang)
J. Integr. Neurosci. 2021, 20(4), 985–991;
https://doi.org/10.31083/j.jin2004099
Submitted: 6 September 2021 | Revised: 29 November 2021 | Accepted: 6 December 2021 | Published: 30 December 2021
Copyright: © 2021 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license (https://creativecommons.org/licenses/by/4.0/).
Abstract
Keywords
Hypoxic-ischemic encephalopathy
Neonate
Magnetic resonance imaging
Arterial spin labeling
Diffusion-weighted imaging
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