Parkinson's disease

Dear Colleagues,

Parkinson’s disease (PD) is a common neurodegenerative disorder, characterized by a clinical symptomatology involving both motor and non-motor symptoms, which may have a major impact on the quality of life. The pathological hallmarks of PD are abnormal accumulation of alpha-synuclein aggregates, Lewy bodies, and Lewy neuritis. The alpha-synucleinopathy in PD involves not only dopaminergic neurons in the substantia nigra pars compacta of the midbrain but also other vulnerable neurotransmitter systems in the central nervous system. To date, the pathophysiological mechanisms underlying various symptoms in patients with PD remain unclear. Additionally, both medication and surgical treatment can relieve the symptoms of patients with PD although the fundamental treatment is still unavailable. This special edition will comprise papers that are pertinent to Parkinson’s disease. The field of Parkinson’s disease has made major advances in recent years and I hope that some of the manuscript in this special edition will reflect on this.

Dr. Ho-Sung Ryu

Guest Editor

Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2200 USD. Submitted manuscripts should be well formatted in good English.