IMR Press / RCM / Volume 17 / Issue 3-4 / DOI: 10.3909/ricm0838
Open Access Review
The Role of Novel Cardiorenal Biomarkers in the Cardiac Catheterization Laboratory for the Detection of Acute Kidney Injury
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1 Department of Medicine, Division of Cardiology, University of Texas Health Science Center at San Antonio, San Antonio, TX
Rev. Cardiovasc. Med. 2016 , 17(3-4), 100–114; https://doi.org/10.3909/ricm0838
Published: 30 September 2016
Abstract
Contrast-induced nephropathy related to cardiac and peripheral vascular procedures is a major problem in the United States and abroad. Measures to prevent and treat this complication have been hampered by the lack of clinical tools to detect acute kidney injury following contrast administration. Emerging novel serum and urinary biomarkers may provide sensitive detection of early kidney injury prior to creatinine elevation and allow for more precise risk stratification and management of patients. This article discusses the biologic and clinical data supporting the development and utility of several promising biomarkers in the management of patients undergoing cardiac catheterization and percutaneous coronary intervention.
Keywords
Contrast-induced acute kidney injury
Cardiac catheterization
Percutaneous coronary intervention
Biomarkers
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