IMR Press / RCM / Volume 23 / Issue 1 / DOI: 10.31083/j.rcm2301006
Open Access Review
Incremental value of the measures of arterial stiffness in cardiovascular risk assessment
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1 Division of Cardiology, Department of Internal Medicine, Boramae Medical Center, Seoul National University College of Medicine, 07061 Seoul, Republic of Korea

Academic Editor: Takatoshi Kasai

Rev. Cardiovasc. Med. 2022 , 23(1), 1;
Submitted: 1 November 2021 | Revised: 24 November 2021 | Accepted: 1 December 2021 | Published: 11 January 2022
Copyright: © 2022 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.

Predicting the occurrence of organ damage and future cardiovascular events is critical to improving patient prognosis through early personalized treatment. Although many tools have been developed and used for individuals’ cardiovascular risk, they have limitations and unmet needs for improved risk stratification. For this purpose, arterial stiffness information can be practical. Arterial walls stiffen with age or prolonged exposure to various noxious stimuli such as high blood pressure, hyperglycemia, inflammation and oxidative stress. Differently from several methods of measuring arterial stiffness, pulse wave velocity (PWV) is most widely used for its non-invasive and easy measurement. It is well authorized that information on arterial stiffness is associated with the development of future cardiovascular events, independent from traditional cardiovascular risk factors, in various patient groups with specific diseases along with the general population. Moreover, when this information of arterial stiffness is associated with other risk stratification tools, it is possible to predict individuals’ cardiovascular risk easier. Herein, we will review the incremental value of the measurement of arterial stiffness in cardiovascular risk assessment when combined with other risk factors such as traditional risk factors, biomarkers, other vascular testing and non-invasive cardiac imaging.

Arterial stiffness
Cardiovascular risk
Incremental value
Pulse wave velocity
Risk assessment
Fig. 1.
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