IMR Press / CEOG / Volume 43 / Issue 2 / DOI: 10.12891/ceog3228.2016
Open Access Original Research
Correlation of ImmunoBead® and ImmunoSphere Immunoglobulin G (IGG) tests on detecting antisperm antibody (ASA) on sperm
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1 Cooper Institute for Reproductive Hormonal Disorders, P.C., Mt. Laurel, NJ
2 Cooper Medical School Of Rowan University, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ (USA)
Clin. Exp. Obstet. Gynecol. 2016 , 43(2), 175–177;
Published: 10 April 2016

Purpose: To determine the correlation with detection of antibody on sperm by a new ImmunoSphereTM Immunoglobulin test vs. ImmunoBeads®. Materials and Methods: A sampling of sperm tested for antisperm antibody (ASA) tested by direct ImmunobeadR assay with levels varying from zero to 100% were compared to the percentage of sperm positive for ASA by a new test using immunospheres. Results: The correlation was not perfect but, in general, there was good correlation. Conclusion: Now that the manufacturer is curtailing the manufacture of immunobeads, it is comforting to see a good correlation with immunospheres.
Antisperm antibodies
Direct immunobead test
Post-coital test
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