IMR Press / EJGO / Volume 39 / Issue 3 / DOI: 10.12892/ejgo3719.2018
Open Access Original Research
Prediction of cervical epithelial lesions level in patients with positive cytologic findings using colposcopic classification Rio De Janeiro 2011
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1 Department of Gynecology and Obstetrics, University Hospital Center "Sestre milosrdnice", Zagreb, Croatia
2 Department of Medical Biochemistry and Hematology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia
Eur. J. Gynaecol. Oncol. 2018 , 39(3), 372–376;
Published: 10 June 2018

Purpose of Investigation: Standard procedure for diagnosis of premalignant cervical changes includes cytological, colposcopic, and histopathological examination. Comparison of the results depends on classifications differences that may influence diagnosis. The aim of this study was to determine efficacy and accuracy of Rio de Janeiro classification in colposcopic prediction of cervical intraepithelial neoplasia (CIN) degree. Materials and Methods: The authors conducted a prospective study over a one-year period. Colposcopic findings were compared with histopathological results. Tumors were classified according to the WHO 2014 criteria. Results: The accuracy of colposcopy is higher for high-grade squamous intraepithelial lesion (HSIL). For major changes and height grade CIN 76% compatibility was found, but in patients without intraepithelial lesion, the compatibility was only 14%. Squamous cell cervical cancer was recognized in 67% of patients and in 33% of patients with cervical planocellular cancer was classified as colposcopic G2 change, which in terms of clinical use can be a satisfactory result. Conclusion: Combination of cytology screening and colposcopy is a good method in the detection of epithelial premalignant and early stages of malignant changes of the cervix.
Cervical intraepithelial neoplasia
Papanicolaou smear
Cervical cancer screening
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