IMR Press / RCM / Volume 22 / Issue 2 / DOI: 10.31083/j.rcm2202056
Open Access Original Research
Independent predictors of in-hospital and 1-year mortality rates in octogenarians with acute myocardial infarction
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1 Cardiology Clinic, Timisoara Municipal Clinical Emergency Hospital, 300024 Timișoara, Romania
2 Multidisciplinary Heart Research Center, Victor Babeș University of Medicine and Pharmacy, 300041 Timișoara, Romania
3 Cardiology Clinic, Timisoara Institute of Cardiovascular Diseases, 300310 Timișoara, Romania
Academic Editor: Gary David Lopaschuk This article belongs to the Special Issue: Contemporary Management of Special Subsets of Acute Coronary Syndromes Patients ().
Rev. Cardiovasc. Med. 2021 , 22(2), 489–497; https://doi.org/10.31083/j.rcm2202056
Submitted: 21 February 2021 | Revised: 22 April 2021 | Accepted: 21 May 2021 | Published: 30 June 2021
Abstract

Older age is known as a negative prognostic parameter in acute myocardial infarction (AMI) patients. In this study, we aimed to explore age-associated differences in treatment protocols, in-hospital and 1-year mortality. This cohort observational study included 277 consecutive AMI patients, separated into 2 groups according to whether their age was 80 years or not. We found that group I patients (aged 80 years) had a notably lower rate of percutaneous coronary intervention (PCI) performed (P < 0.0001) and a notably higher in-hospital death rate (P < 0.003). The multivariate logistic regression analysis found that three variables were independent predictors of in-hospital mortality: age 80 years (P < 0.0001), LVEF <40% (P < 0.0001), and Killip class 3 (P < 0.0001). The 1-year death rate was again significantly higher in group I patients (P < 0.001) and was independently predicted by the triple-vessel coronary artery disease (P = 0.004) and an LVEF <40% at admission (P = 0.001). The 1-year readmission rate was superior in group I (P < 0.01) and independently predicted by an age 80 years (P < 0.001), and an history of congestive heart failure (P < 0.0001) or permanent atrial fibrillation (P < 0.001). We concluded that patients aged 80 benefit less often from a PCI and have higher rates of in-hospital mortality, as well as of 1-year readmission and mortality rates.

Keywords
Acute myocardial infarction
Age ≥80 years
Treatment
Prognosis
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