Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Argyrophilic Proteins of Nucleolar Organizer Regions (AgNORs) in fallopian tube carcinomas
Forty-four patients diagnosed with primary cancer of the fallopian tube (PFTC) were analyzed with regard to AgNORs expression, morphological classification. clinical stage and survival rate. Twenty-seven patients were FIGO stage I, 7 FIGO II and 10 FIGO III. Histological classification of PFTC revealed 18 endometrioid types, 9 serous, 7 undifferentiated, 6 urothelial, 2 clear cell and 2 another type of (intestinal, squamous cell) cancer. Histological grading revealed 11 G1, 16 G2 and 17 G3 tumors. The number of AgNORs per nucleus ranged from 1 to 7, mean 2.5 ± 0.77. The smallest number of silver stained NORs was observed in the endometrioid type (mean 2.32 ± 0.62) and the biggest number of AgNORs in undifferentiated carcinoma (mean 3.05 ± 0.82). There was no correlation between number of AgNORs and AgNOR area/nuclear area ratio and survival (p = 0.71), histological stage or histological type of PFTC. There was a correlation between the number of AgNORs among tumors with histological grade 1 and grade 3 (p = 0.023), and grade 2 and grade 3 (p = 0.045). However, there was no correlation between AgNOR number and survival rate in these groups.