IMR Press / CEOG / Volume 39 / Issue 1 / pii/1630475477948-53689130

Clinical and Experimental Obstetrics & Gynecology (CEOG) is published by IMR Press from Volume 47 Issue 1 (2020). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research
Pregnancy outcome following fresh vs frozen embryo transfer into gestational carriers using a simplified slow freeze protocol
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1 The University of Medicine and Dentistry of New Jersey, Cooper Medical School of Rowan University Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology Division of Reproductive Endocrinology & Infertility, Camden, NJ (USA)
Clin. Exp. Obstet. Gynecol. 2012, 39(1), 23–24;
Published: 10 March 2012
Abstract

Purpose: To compare pregnancy rates following fresh vs frozen embryo transfer into gestational carriers. Methods: Choice of deferring fresh embryo transfer and cryopreserving the embryos vs fresh transfers was not randomized but based on circumstances. The cryopreservation protocol used a simplified slow cool technique avoiding the planar programmable freezer and using a one-step removal of the cryoprotectant. Results: The live delivered pregnancy rate was 51.0% (49/96) for fresh embryo transfer vs 34.3% for transfers of frozen thawed embryos in gestational carriers not having a fresh embryo first. Conclusions: Using the simplified slow cool cryopreservation protocol with a one-step removal of cryoprotectants pregnancy rates are comparable to what is found in women of similar ages undergoing controlled ovarian hyperstimulation followed by IVF-ET. However, when transferring to a gestational carrier the live delivered pregnancy rates are 50% higher with fresh embryo transfer.
Keywords
Frozen embryo transfer
Fresh embryo transfer
Gestational carrier
Pregnancy rate
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