IMR Press / CEOG / Volume 41 / Issue 4 / DOI: 10.12891/ceog16702014
Open Access Original Research
Increased platelet count in severe peritoneal endometriosis
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1 Department of Obstetrics and Gynecology
2 Department of Biostatistic and Medical Informatics Dicle University, School of Medicine, Diyarbakir (Turkey)
Clin. Exp. Obstet. Gynecol. 2014 , 41(4), 423–425; https://doi.org/10.12891/ceog16702014
Published: 10 August 2014
Abstract

Objective: Platelet count (PC) is higher in chronic inflammatory diseases. The aim of this study was to evaluate the PC in patients with severe pelvic endometriosis. Materials and Methods: Patients with advanced stage pelvic endometriosis were retrospectively evaluated in a tertiary center between January 2009 and December 2011. Patients with pelvic endometriosis were divided into two groups; advanced stage peritoneal endometriosis were classified as Group 1 (n = 28). Group 2 consisted of 29 patients which had ovarian endometrioma without clinically apparent peritoneal endometriosis foci. Group 3 included 51 women as control subjects. PC between the groups was tested by Student’s t test. The mean values of three groups were analyzed by using one way ANOVA test followed post-hoc test Bonferroni. Results: PC in patients with pelvic endometriosis were found to be higher from the control group (290 ± 67 109/l; 264 ± 63 109/l, respectively; p = 0.038). Patients with peritoneal endometriosis (Group 1) had significantly higher PCs compared with the healthy controls (309 ± 65 109/l; 264 ± 63 109/l; respectively; p = 0.011). Conclusion: Increased PC in advanced stage pelvic endometriosis may be a sign of increased systemic inflammation. The systemic inflammation may be more apparent in advanced stage peritoneal endometriosis.
Keywords
Endometriosis
Inflammation
Platelet count
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