IMR Press / CEOG / Volume 44 / Issue 2 / DOI: 10.12891/ceog3385.2017
Open Access Case Report
Virtopsy in conjoined ischiopagus twins
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1 Unit of Obstetrics and Gynecology, IRCCS A.O.U. San Martino IST, Genoa, Italy
2 Department of Pathology, University of Genoa and IRCCS A.O.U. San Martino IST, Genoa, Italy
3 Department of Radiology, IRCCS A.O.U. San Martino IST, Genoa, Italy
4 Department of Pathology, University of Genoa and IRCCS G. Gaslini Institute, Genoa, Italy
Clin. Exp. Obstet. Gynecol. 2017 , 44(2), 288–291; https://doi.org/10.12891/ceog3385.2017
Published: 10 April 2017
Abstract

Purpose of investigation: To propose a multidisciplinary protocol for postmortem disclosure of complex fetal malformations, comparing ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and autopsy in a case of conjoined ischiopagus twins. Materials and Methods: A screening second-trimester ultrasound diagnosed ischiopagus twins at 20 gestational weeks in a 31- year-old woman without any previous ultrasound examination. The couple decided for pregnancy termination. The formalin-fixed fetuses underwent full-body CT, MRI, and autopsy. Results: ultrasound accurately diagnosed ischiopagus twins. CT was very accurate in the description of bone components. MRI allowed better visualization of the visceral organs than CT. Only autopsy could disclose the aspect of the two gastrointestinal tracts and the external genitalia. Conclusions: Prenatal ultrasound represents the standard diagnostic exam for conjoined twins. CT-MRI virtual autopsy (virtopsy) may be an option if the couple refuses to authorize necropsy or may be useful to plan a minimally invasive autopsy preserving the external phenotype.
Keywords
Autopsy
Computed tomography
Conjoined twins
Magnetic resonance imaging
Ultrasound
Virtopsy
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