IMR Press / CEOG / Volume 45 / Issue 2 / DOI: 10.12891/ceog3873.2018
Open Access Original Research
The expression of Nuclear Factor-κB in a rat model of polycystic ovary syndrome
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1 Department of Gynecology and Obstetrics, The Affiliated Union Hospital, Fujian Medical University, Fuzhou, China
Clin. Exp. Obstet. Gynecol. 2018 , 45(2), 276–279; https://doi.org/10.12891/ceog3873.2018
Published: 10 April 2018
Abstract

Objective: To discuss the effect of Nuclear Factor-κB (NF-κB) in polycystic ovary syndrome (PCOS). Materials and Methods: Thirty female SD rats were divided into a control group (n=15) and a PCOS group (n=15). The expression of NF-κB in ovaries of each group was monitored by way of immunohistochemistry and quantitative PCR. Results: The expression of NF-κB p65 in ovaries by immunohistochemical and fluorescence quantitative PCR shows no significant difference between the two groups (p > 0.01). Conclusion: The pathogenesis of this research model has no obvious association with NF-κB.
Keywords
Polycystic ovary syndrome
NF-κB
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