IMR Press / CEOG / Volume 45 / Issue 2 / DOI: 10.12891/ceog3889.2018
Open Access Original Research
Clinical characteristics and pregnancy outcomes in parturients with pulmonary hypertension: experience with 39 consecutive cases from China
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1 Department of Obstetrics and Gynecology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China
Clin. Exp. Obstet. Gynecol. 2018 , 45(2), 257–261; https://doi.org/10.12891/ceog3889.2018
Published: 10 April 2018
Abstract

Purpose: The authors aimed to understand the clinical characteristics of pulmonary hypertension (PH) with pregnancy and pregnancy outcomes in Chinese population. Materials and Methods: The authors retrospectively analyzed 39 parturients with PH. The patients were divided into mild PH group (n = 20) and severe PH group (n = 19). They compared some clinical characteristics, as well as maternal and fetal outcomes between the mild and severe PH groups. Results: The diagnostic rate of PH before pregnancy was 7.7% and the overall maternal mortality was 15.4%. There was no significant difference in age, body mass index, average termination of gestation weeks, and New York Heart Association functional class pre-pregnancy between the mild and severe PH groups. The mortality in the severe PH group (31.6%) was significantly higher than that in the mild PH group (0%) (p < 0. 05). In addition, the occurrence rate of post-partum haemorrhage (PPH) and natality of low-birth weight neonates (LBWN) were significantly higher in the severe PH group (21.1%; 36.8%) than that in the mild PH group (0%; 10%) (p < 0. 05), respectively. Conclusion: The overall mortality of parturients with PH is high and severe PH increase the risk of death, occurrence rate of PPH, and natality of LBWN.
Keywords
Pregnancy
Pulmonary hypertension
Maternal mortality
Post-partum haemorrhage
Low-birth weight neonates
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