- Academic Editor
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†These authors contributed equally.
Background: There are few studies evaluating the effects of number and quality of transferred blastocysts on birth outcomes in frozen-thawed transfer cycles. Methods: A retrospective study was conducted, encompassing 5493 frozen-thawed blastocyst transfer cycles
from January 2019 to June 2021. The cycles were categorized into five groups
based on the number and quality of transferred blastocysts, as well as
trichotomized based on maternal age brackets. Pregnancy outcomes such as
implantation rate (IR), clinical pregnancy rate (CPR), multiple pregnancy rate
(MPR), abortion rate (AR), live birth rate (LBR), and neonatal characteristics
were compared and statistically analyzed. Results: The data revealed
that maternal age, quality and number of the transferred blastocysts exerted a
demonstrable impact on both pregnancy and birth outcomes. Within the same
blastocyst transfer groups, it was noted that IR, CPR, and LBR exhibited a
progressive decline as a function of advancing maternal age. Amplifying the
number of homogeneously graded blastocysts for transfer did not conspicuously
elevate CPR and LBR; however, it led to a statistically significant escalation in
MPR (p