- Academic Editor
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Background: Parvovirus B19 (B19V) infection is
ever-present and contagious. It is acquired during childhood and adolescence, but
can occur at any age. B19V infection occurs in endemic epidemic mode in temperate
zones in winter and spring. B19V infections, although often asymptomatic in
pregnant women, can be responsible for hydrop fetalis, fetal anemia, and death in
utero. This study will evaluate the seroprevalence of immunoglobulin G (IgG)
antiparvovirus in pregnant women in Marrakesh city in Morocco, and to find out
the possible risk factors associated with B19V infections.
Methods: We randomly selected 100 pregnant women from the
Zerktouni hospital in Marrakesh. Socio-demographic characteristics and background
were collected using a questionnaire. Serologic tests were carried out by
searching for immunoglobulin G antibodies via the
ParvovirusVirclia® IgG Chemiluminescencemonotest kits (Vircell
Microbiologist, Granada, Spain) at the Bacteriology-Virology laboratory of the
Avicenna Military Hospital in Marrakesh. Results: The median
age of study participants was 27 (interquartile range (IQR): 17–43) years. Of
100 pregnant women 8%, 38% and 54% were in the first, second and third
trimester respectively. The majority 96% of women were from urban areas.
Nineteen percent (19%) of them had a history of spontaneous abortion. Of 100
pregnant women, the overall prevalence of IgG was 51 (51%). The average age of
participants with positive serology was 26.45 years, and the mean age of those
with negative serology was 28.98 years. The immunity against the virus was higher
in young pregnant women. Twenty five (25%) women tested positive for B19V
antibodies in the third trimester of pregnancy, implying immunity for the virus.
The results of logistic regression showed insignificant association between the
prevalence of B19V IgG antibodies and the demographic and obstetrical factors
except for the having a child under 6 years factor (