- Academic Editor
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Background: To explore the correlation of pre-pregnancy body mass index
(BMI) and gestational weight gain (GWG) with the occurrence of birth defects.
Methods: Clinical data of pregnant women were collected in Zhuzhou
Central Hospital from January 2019 to December 2021. A total of 10,086 newborns,
including 175 newborns with birth defects. Birth defect cases were identified,
and 350 cases of pregnant women without birth defects were randomly selected as
the control group by control case matching (1:2). Clinical baseline data were
compared between the two groups, and logistic single-factor analysis was
performed to examine the correlation between pre-pregnancy BMI, GWG, and birth
defects. Results: The study consisted of a total of 175 cases of birth
defects, including circulatory system 114 (65.14%) cases, musculoskeletal system 34 (19.43%) cases, urinary system 15 (8.57%) cases, and 12 (6.86%) cases of other birth defects.
There were no statistical
differences in parity between the two groups (p