- Academic Editor
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Background: We conducted this study to investigate adverse pregnancy
outcomes of hepatitis B virus infection coexistng with intrahepatic cholestasis
in pregnant women, along with identifying associated risk factors.
Methods: We retrospectively collected study data from Beijing Youan
Hospital in China spanning January 2014 to December 2021. The study included 220
patients, divided into two groups: Group I consisted of 110 patients with
hepatitis B virus infection and intrahepatic cholestasis during pregnancy, while
Group II comprised 110 patients with hepatitis B virus infection alone. Maternal
demographics, laboratory values, obstetric complications, and adverse pregnancy
outcomes were collected and analyzed between Groups I and II. To investigate the
features of hepatitis B virus infection with intrahepatic
cholestasis in pregnancy patients further, we also evaluated risk factors of
adverse pregnancy outcomes in Group I. Results: Adverse pregnancy
outcomes, including preterm birth (