Fig. 1.Results of tract-based spatial statistics analyses
comparing fractional anisotropy (FA) values of patient and control groups and the
standard template of the Johns Hopkins University HU diffusion tensor
imaging-based white matter atlases. (A) T2-weighted brain magnetic resonance
images at the time of diffusion tensor image scanning in representative patients
with unilateral right-intracerebral hemorrhage (41-year-old female) and
left-intracerebral hemorrhage (50-year-old male). (B) The blue and red voxels
represent areas with significantly lower mean FA values in the patient group than
in the control group. (C) The 27 regions of interest (ROIs): (1) Middle
cerebellar peduncle, (2) Pontine crossing tract, (3) Genu of corpus callosum, (4)
Body of corpus callosum, (5) Splenium of corpus callosum, (6) Column and body of
fornix, (7) Corticospinal tract, (8) Medial lemniscus R, (9) Inferior cerebellar
peduncle, (10) Superior cerebellar peduncle, (11) Cerebral peduncle, (12)
Anterior limb of internal capsule, (13) Posterior limb of internal capsule, (14)
Retrolenticular part of internal capsule, (15) Anterior corona radiata, (16)
Superior corona radiata, (17) Posterior corona radiata, (18) Posterior thalamic
radiation (including the optic radiation), (19) Sagittal stratum (include
inferior longitudinal fasciculus and inferior fronto-occipital fasciculus), (20)
External capsule, (21) Cingulum (cingulate gyrus), (22) Cingulum, (23) Fornix
(crus), (24) Superior longitudinal fasciculus, (25) Superior fronto-occipital
fasciculus, (26) Uncinate fasciculus, and (27) Tapetum. Moderate negative
correlations between intracerebral hemorrhage volume and the fractional
anisotropy value (red rectangular boxes) are observed in the sagittal stratum
(ROI 19) and the tapetum (ROI 27).