Background: Paediatric Traumatic Brain Injury (TBI) has received less
research attention compared to TBI in adults, despite its potential morbidity in
all ages. Our aim was to determine whether neutrophil to lymphocyte ratio (NLR),
platelet to lymphocyte ratio (PLR) and glucose levels at admission can reliably
predict the need for imaging in children presenting with mild TBI.
Methods: We retrospectively reviewed the clinical records of paediatric
patients who presented in the emergency department with mild TBI within a 5 year
period and had undergone computed tomography (CT) scan of the head.
Results: Overall, 43 eligible patients were included in the study, with
falls being the most commonly reported cause of injury. Twenty-three children had
positive CT findings. Patients with abnormal CT findings were found to have
higher NLR ratios compated with patients with normal CT, with the mean NLR on
admission being 5.2
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Open Access
Original Research
Blood Biomarkers for Prediction of Positive CT Findings in Mild Traumatic Brain Injury in Paediatric Population
Timoleon Siempis1, Pavlos A Georgalis1, Georgios Lianos2, Georgios Kafritsas1, Dimitrios Metaxas1, Eleutherios-Spyridon Alexiou1, Jiolanda Zika1, Athanasios Sotiropoulos1, George A Alexiou1,*, Spyridon Voulgaris1
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1
Department of Neurosurgery, University Hospital of Ioannina, 45500 Ioannina, Greece
2
Department of Surgery, University Hospital of Ioannina, 45500 Ioannina, Greece
*Correspondence: galexiou@uoi.gr (George A Alexiou)
J. Integr. Neurosci. 2023, 22(4), 91;
https://doi.org/10.31083/j.jin2204091
Submitted: 27 February 2023 | Revised: 16 April 2023 | Accepted: 20 April 2023 | Published: 7 July 2023
Copyright: © 2023 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract
Keywords
biomarkers
emergency department
CT
Glasgow Coma Scale
head trauma
mild traumatic brain injury
neutrophil-to-lymphocytes ratio
radiation exposure
paediatrics
neurosurgery
Figures
Fig. 1.