IMR Press / RCM / Volume 15 / Issue 4 / DOI: 10.3909/ricm0775
Open Access Review
Advanced Lipid Testing: When, Why, and In Whom?
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1 The David Geffen School of Medicine at UCLA, University of California, Los Angeles, Los Angeles, CA
2 Methodist Physicians, San Antonio, TX
3 University of Pennsylvania Health System, Philadelphia, PA
4 Baylor University Medical Center at Dallas, Baylor Heart and Vascular Institute, Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, TX; The Heart Hospital, Plano, TX
Rev. Cardiovasc. Med. 2014 , 15(4), 310–319; https://doi.org/10.3909/ricm0775
Published: 30 December 2014
Abstract
Atherosclerotic cardiovascular disease is a leading cause of morbidity and mortality in developed countries. The management of blood cholesterol with the use of statin drugs in at-risk patients is a pillar of medical therapy for the primary and secondary prevention of cardiovascular disease. Although the standard lipid panel is adequate to accurately assess cardiovascular disease risk in most patients, there are some situations in which conventional cholesterol testing does not fully identify cardiovascular risk or reflect disease progression. A number of advanced lipid tests can assist the clinician when assessing a patient's cardiovascular disease risk, including measurement of low-density lipoprotein particle number.
Keywords
Atherosclerotic cardiovascular disease
Risk
Low-density lipoprotein cholesterol
Lowdensity lipoprotein particle number
Statin therapy
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