Academic Editor: Peter A. McCullough
Left ventricular outflow tract (LVOT) obstruction and systolic anterior motion
(SAM) of the mitral valve (MV) occurs in 70% of hypertrophic cardiomyopathy
(HCM) patients. In individuals undergoing septal myectomy, concomitant MV surgery
is considered for SAM with residual LVOT obstruction or mitral regurgitation
(MR); however, the optimal approach remains debated. A literature search was
performed in Pubmed, EMBASE, Ovid, and the Cochrane library of published articles
through June 2021 reporting on combined septal myectomy and edge-to-edge MV
repair for obstructive HCM. Continuous variables were weighted and compared using
a student’s t-test, and categorical variables using a chi-square test
with Yates correction. Six studies with 158 total patients were included. The
mean follow-up was 2.8