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- Academic Editors
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Background: Despite gradually increasing evidence for
pre-rehabilitation for heart valve surgery, it remains underused, especially in
developing countries with limited resources. The study aimed to investigate the
feasibility and effects of an innovative three-day pre-rehabilitation bundle for
patients undergoing elective heart valve surgery. Methods: This was a
single-center, assessor-blind, randomized clinical trial. A total of 165 patients
were randomly assigned to either usual care (control group, n = 83) or usual care
with an additional 3-day pre-rehabilitation bundle (Three-day of Inspiratory
muscle training, aerobic Muscle training, and Education (TIME) group, n = 82).
The main outcome of the study was the incidence of postoperative pulmonary
complications (PPCs). Secondary outcomes included the feasibility of the
intervention, duration of the non-invasive ventilator, length of stay, and
PPCs-related medical costs on discharge. Results: Of 165 patients
53.94% were male, the mean age was 63.41 years, and PPCs were present
in 26 of 82 patients in the TIME group and 44 of 83 in the control group (odds
ratio (OR), 0.60; 95% CI, 0.41–0.87, p = 0.006). The feasibility
of the pre-rehabilitation bundle was good, and no adverse events were observed.
Treatment satisfaction and motivation scored on 10-point scales, were 9.1