Background: Several technical limitations exist in angiography
procedures, including suboptimal visualization of a particular location and
angiography only providing information about the contour of the vascular lumen,
while intravascular ultrasound (IVUS) provides information regarding wall
composition on coronary vascular lesions. With recent trials demonstrating IVUS
benefits over standard angiography, our meta-analysis aimedto evaluate and
summarize the current evidence on whether IVUS-guided drug-eluting stent (DES)
placement resulted in better outcomes than the angiography-guided DES placement
in patients with left main coronary artery (LMCA) disease.
This meta-analysis aimed to analyze the current evidence on the IVUS-guided and angiography-guided drug-eluting stent (DES)
placement in patients with LMCA disease. Methods: Literature searching
was performed using Scopus, Embase, PubMed, EuropePMC, and Clinicaltrials.gov
using PRISMA guidelines. The intervention group in our study are patients
undergoing IVUS-guided percutaneous coronary intervention (PCI) and the control
group are patients undergoing angiography alone-guided PCI. Cardiovascular
mortality, all-cause mortality, target lesion revascularization, myocardial
infarction, and stent thrombosis were compared between the two groups.
Results: There were 11 studies comprising 24,103 patients included in
this meta-analysis. IVUS-guided PCI was associated with lower cardiovascular
mortality (hazard ratio (HR) 0.39 [95% CI 0.26, 0.58], p
Announcements
Open Access
Systematic Review
Intravascular Ultrasound versus Angiography Guided Drug Eluting Stent Implantation in Patients with Left Main Coronary Artery Disease – A Systematic Review and Meta-Analysis
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1
Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Padjadjaran, 40161 Bandung, Indonesia
*Correspondence: kevinkarim.official@gmail.com (Kevin Karim)
Rev. Cardiovasc. Med. 2024, 25(1), 32;
https://doi.org/10.31083/j.rcm2501032
Submitted: 26 July 2023 | Revised: 5 September 2023 | Accepted: 14 September 2023 | Published: 22 January 2024
Copyright: © 2024 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract
Keywords
angiography
intravascular ultrasound
percutaneous coronary intervention
left main coronary artery disease
mortality
infarction
Graphical Abstract
Figures
Fig. 1.