*Xiaohua Li is corresponding author and Guishuang Ying is co-corresponding author.
Academic Editors: Shikun He and Graham Pawelec
Background: Cumulative evidence suggests that the risk of eye tumors
varies among different age groups and populations. The purpose of the present
study was to assess the age distribution of eye tumors in China.
Methods: In this retrospective study, the age distribution of various
types of eye tumors was analyzed on surgically excised and histologically
confirmed specimens obtained from 4492 patients (4526 eyes), collected between
2001 and 2017. Results: Of the 4526 specimens, 3156 eyes (69.7%) had
benign eye tumors, while 1370 eyes (30.3%) had malignant tumors. The
age-specific incidence of eye tumors was characterized by a bimodal distribution,
one peak occurred at age 0–9 years (19.7%) and the other at 50–59 years
(14.7%) of age. Malignant eyelid tumors were very rare under the age of 20
years, but increased to 78% of all eyelid tumors by the age of 70 years.
Children aged 0–9 years old were 6.5 times as likely to have a malignant eye
tumor (95% CI, 4.1–10.4) as those aged 10–19 years. The age-related variation
of eye tumors was also observed in the top ten categories of both benign
(p