Circadian Rhythms in Health and Disease - Volume 2

Dear Colleagues,

Circadian clocks influence physiological routes and pathophysiological conditions. Intrinsic body clocks exist in almost all organisms, but are particularly complex in humans. The circadian system is a key regulatory factor for several physiological activities and its disorder might have severe consequences on human health. The autonomous circadian timing system is essential for the adjustment to recurring environmental changes as food availability. In healthy subjects, circadian rhythms have a strong influence in the regulation of sleep, metabolism, and different systems (cardiovascular, nervous, and immune).

These circadian clocks are also important in the etiology and treatment of various diseases. Modern society way of life with artificial light, might turn biological night into day, producing circadian misalignment. The mismatch of the intrinsic clock time with the environmental daytime, might increase in some situations, as in the case of shift workers or during jetlag. This circadian desynchronisation can be associated with the risk of some diseases and can influence treatment response. Chronotherapeutics might be included as a treatment plan, with the aim of a balanced relationship between the circadian system and its environment. In addition, insights into the circadian regulation of human physiology and its influence in the response to disease might provide opportunities for the discovery of new treatment strategies.

This Special Issue will center its attention on both fundamental research and translational studies, aiming to comprehensively explore how the regulation of circadian rhythms contributes to health and disease. We welcome submissions of original research articles, review papers, and short communications.

Prof. Dr. Manuel Martínez-Sellés
Guest Editor

Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2500 USD. Submitted manuscripts should be well formatted in good English.