Pathophysiological Mechanisms and Efficient Management of Neurodegenerative Diseases

Dear Colleagues,

Despite much effort so far to manage neurological diseases, it remains challenging to identify their multimodal development and the specific neurophysiologic pathways in the brain that affect the patient. Although significant progress has been made, neurodegeneration is difficult to treat and to diagnose holistically at an early stage. A cure has yet to been found for these disorders, prompting researchers to develop hybrid computational models for the detection of early symptoms, and for alternative methods and products to delay the development of disease. More research is required to identify biomarkers and to develop effective drugs that delay disease symptoms and lesions. As shown with Alzheimer's disease, the unsuccessful clinical trials for new holistic treatments and for drugs with fewer side-effects has revealed the need for precision medicine. This is required to address the increasing burden of comorbidities, for the design of new prognostic and treatment tools, and to improve the global health market for the millions of end-users. 

In this special issue, we welcome neuroscientists to contribute articles that describe the efficient management of neurodegeneration, the genetic mechanisms, potential comorbidities, commonalities with related disorders, novel therapeutic approaches, as well as economic-social and ethical issues. All the papers invited by guest editors will be provided 30% discount.

Dr. Ghulam Md Ashraf and Dr. Athanasios Alexiou
Guest Editors

Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2200 USD. Submitted manuscripts should be well formatted in good English.