IMR Press / RCM / Volume 19 / Issue 4 / DOI: 10.31083/j.rcm.2018.04.4081
Open Access Case Review
Pitfalls in the diagnosis and initial management of acute cerebral venous thrombosis
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1 Department of Neurology, Neuroscience Center, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University. No.3 East Qingchun Rd., Hangzhou, Zhejiang, China, 310020
2 Department of Neurology, Wen Ling Hospital of Traditional Chinese Medicine. No.21 North Mingyuan Rd. Taizhou, Zhejiang, China, 317500
3 Department of Radiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University. No.3 East Qingchun Rd., Hangzhou, China, 310020
4 Department of Neurology, Shao Xing No. 2 People’s Hospital. No.147 Yanan Rd. Shaoxing, Zhejiang, China, 312000
Rev. Cardiovasc. Med. 2018 , 19(4), 129–133; https://doi.org/10.31083/j.rcm.2018.04.4081
Published: 30 December 2018
Abstract
Cerebral venous thrombosis is an important etiology of stroke in young patients. Its clinical manifestations are variable and based on different involved venous or sinus processes. Cerebral venous thrombosis could mimic ischemic infarction and is easy to misdiagnose. Although many patients have favorable outcomes, delayed or incorrect diagnosis due to atypical symptoms may lead to a poor prognosis. Here we present a case of a 33-year-old woman with transient headache and recurrent right extremity weakness whose symptoms progressed and were sustained in the hospital. She was diagnosed with ischemic infarction and recombinant tissue plasminogen activator (rtPA) thrombolysis was performed. However, her symptoms progressed, and intracranial hematoma was found on a computed tomography scan. Ruling out other hemorrhage etiology, we confirmed the presence of cerebral venous thrombosis using magnetic resonance venography. She underwent mechanical thrombectomy and her condition improved thereafter. This case raises the awareness that in young woman patients on oral contraceptives with neurological deficits and headache, cerebral venous thrombosis is a considerable diagnosis. A contrast CT or MRI scan should be ordered in the early course of evaluation, which can help the physician to make the right clinical decision.
Keywords
Cerebral venous thrombosis
recombinant tissue plasminogen activator
catheter-based local thrombolysis
thrombectomy
Funding
81400926/The Natural Science Foundation of China
2018RC045/Health General Research Project of Zhejiang Province, China
LY19H090027/The Natural Science Foundation of Zhejiang Province of China
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