Background: Patients on chronic dialysis are less likely to be treated
with percutaneous coronary intervention (PCI) for acute myocardial infarction
(AMI). This is due to the lack of evidence from randomized trials, concerns about
possible PCI-related side effects, and multimorbidity. Therefore, routine use of
PCI for treatment of dialysis patients with AMI remains an unresolved issue.
Methods: We analyzed data of patients on chronic dialysis hospitalized
with AMI from 2003 to 2018, by using the administrative Lombardy Health Database
(Italy). Patients were grouped according to whether they underwent or not PCI
during index hospitalization. The primary outcome was in-hospital mortality,
1-year mortality was the secondary endpoint. Results: During the study
period, 265,048 patients were hospitalized with AMI. Of them, 3206 (1.2%) were
on chronic dialysis (age 71
Announcements
Open Access
Original Research
Prognostic Impact of Percutaneous Coronary Intervention in Chronic Dialysis Patients with Acute Myocardial Infarction: Findings from the Lombardy Health Database
Nicola Cosentino1, Simonetta Genovesi2,3,*, Alice Bonomi1, Filippo Trombara1, Monica Ludergnani1, Olivia Leoni4, Francesco Bortolan4, Piergiuseppe Agostoni1,5, Giancarlo Marenzi1
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1
Centro Cardiologico Monzino, IRCCS, 20138 Milan, Italy
2
School of Medicine and Surgery, Nephrology Clinic, Milano-Bicocca University, 20900 Monza, Italy
3
Istituto Auxologico Italiano, IRCCS, 20133 Milan, Italy
4
Regional Epidemiological Observatory, Lombardy Region, 20100 Milan, Italy
5
Cardiovascular Section, Department of Clinical Sciences and Community Health, University of Milan, 20159 Milan, Italy
*Correspondence: simonetta.genovesi@unimib (Simonetta Genovesi)
Rev. Cardiovasc. Med. 2023, 24(5), 135;
https://doi.org/10.31083/j.rcm2405135
Submitted: 2 January 2023 | Revised: 1 April 2023 | Accepted: 10 April 2023 | Published: 28 April 2023
(This article belongs to the Special Issue Coronary Artery Disease in Dialysis Patients)
Copyright: © 2023 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract
Keywords
acute myocardial infarction
chronic dialysis
percutaneous coronary intervention
mortality
administrative database
Funding
NET-2016-02364191/Italian Ministry of Health and the Lombardia Region
EASY-NET/Italian Ministry of Health and the Lombardia Region
Figures
Fig. 1.