IMR Press / RCM / Volume 25 / Issue 4 / DOI: 10.31083/j.rcm2504146
Open Access Original Research
Outcomes of Mitral Valve Repair for Posterior Leaflet Prolapse, Anterior Leaflet Prolapse, and Bileaflet Prolapse
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1 Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, 100069 Beijing, China
2 Department of Ultrasound, Beijing Anzhen Hospital, Capital Medical University, 100069 Beijing, China
3 Department of Pediatric Cardiac Center, Beijing Anzhen Hospital, Capital Medical University, 100069 Beijing, China
*Correspondence: jiangangwang@ccmu.edu.cn (Jiangang Wang)
Rev. Cardiovasc. Med. 2024, 25(4), 146; https://doi.org/10.31083/j.rcm2504146
Submitted: 14 December 2022 | Revised: 10 April 2023 | Accepted: 17 April 2023 | Published: 17 April 2024
Copyright: © 2024 The Author(s). Published by IMR Press.
This is an open access article under the CC BY 4.0 license.
Abstract

Background: Mitral valve repair (MVr) is an effective treatment for degenerative mitral regurgitation (DMR).And the outcomes and repair rates for posterior leaflet prolapse (PLP), anterior leaflet prolapse (ALP), and bileaflet prolapse (BLP) vary. This study aimed to compare the outcomes of mitral valve repair for patients with PLP, ALP, and BLP. Methods: From 2010 to 2019, 1192 patients with degenerative mitral valve regurgitation underwent surgery at our hospital. And 1069 patients were identified. The average age of all patients was (54.74 ± 12.17) years old for all patients. 273 patients (25.5%) had ALP, 148 patients (13.8%) had BLP, and 648 patients (60.6%) had PLP. All patients were followed up for an average duration of 5.1 years. We compared the outcomes of patients with ALP, PLP, and BLP. Results: Patients with ALP were the youngest of the 3 groups and had the highest prevalence of atrial fibrillation. Patients with PLP had the highest prevalence of hypertension, whereas patients with BLP and ALP had larger left ventricular end-diastolic and left ventricular end-systolic diameters. ALP and BLP repairs had a longer cardiopulmonary bypass and aortic cross-clamp time.10 patients dead in-hospital, 5 patients had PLP, 3 had ALP, and 2 had BLP. The 10-year survival cumulative incidences of reoperation among ALP, BLP, and PLP repairs were not significantly different. ALP repair still had higher cumulative incidences of recurrent mitral regurgitation (MR) compared to PLP. Conclusions: The rates of long-term survival and freedom from reoperation were not significantly different among patients with ALP, BLP, and PLP. ALP repair has higher cumulative incidences of recurrent MR compared to PLP.

Keywords
degenerative mitral valve regurgitation
posterior leaflet prolapse
anterior leaflet prolapse
Figures
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