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New Insight into Extracellular Vesicles in Human Diseases

Submission deadline: 15 January 2022
Special Issue Editors
Silvia S. Barbieri
Unit of Brain-Heart axis: Cellular and Molecular Mechanisms, Centro Cardiologico Monzino IRCCS, via Parea 4, 20138 Milan, Italy
Interests: Thrombosis; Platelets; Coagulation; Extracellular Vesicles; Neurotrophins; Oxidative Stress; Animal Models; Cellular Models; Behavioural and Psychological Factors; Vascular Biology
Marta Zarà
Unit of Brain-Heart axis: Cellular and Molecular Mechanisms, Centro Cardiologico Monzino IRCCS, via Parea 4, 20138 Milan, Italy
Interests: Platelets; Extracellular Vesicles; Cell Signalling
Special Issue Information

Dear Colleagues,

Extracellular vesicles (EVs), including exosomes, microvesicles and apoptotic bodies, are released by most cell types and detectable in the body fluids. They carry lipids, proteins, and nucleic acids, according to their cellular origin. EVs transfer this cargo to other cells playing a key role into cell-to-cell and organs communication in both physiological and pathological conditions. The properties of EVs have suggested their application as prognostic and diagnostic tool, as well as their use as therapeutic tool in tissue regeneration and drug delivery.

The purpose of this Special Issue is to provide insights into current knowledge regarding the roles of extracellular vesicles in human diseases, and both reviews and original articles are welcomed. Reviews should provide a state-of-the-art overview of extracellular vesicles in the context of human diseases and may also highlight new technical approaches for isolation and characterization EVs from biological fluids, as well as their application as diagnostic and therapeutic tool. Original Articles should address the physiopathology of extracellular vesicles in humans and experimental models, underling their potential role in pathogenesis, diagnosis, and therapeutics, including new findings on the use of EVs as biomarkers and/or as a new therapeutic strategy.

Dr. Silvia S. Barbieri and Dr. Marta Zarà

Guest Editors

Extracellular Vesicles
Lipids and Proteins
MicroRNAs and Noncoding RNA
Chronic Diseases and Acute Diseases
Therapeutic Potential
Manuscript Submission Information

Manuscripts should be submitted via our online editorial system at by registering and logging in to this website. Once you are registered, click here to start your submission Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2500 USD. Submitted papers should be well formatted and use good English.

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