- Academic Editor
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†These authors contributed equally.
Background: Delayed encephalopathy after acute carbon monoxide
poisoning (DEACMP) is a severe complication that can arise from acute carbon
monoxide poisoning (ACOP). This study aims to identify the independent risk
factors associated with DEACMP and to develop a nomogram to predict the
probability of developing DEACMP. Methods: The data of patients
diagnosed with ACOP between September 2015 and June 2021 were analyzed
retrospectively. The patients were divided into the two groups: the DEACMP group
and the non-DEACMP group. Univariate analysis and multivariate logistic
regression analysis were conducted to identify the independent risk factors for
DEACMP. Subsequently, a nomogram was constructed to predict the probability of
DEACMP. Results: The study included 122 patients, out of whom 30
(24.6%) developed DEACMP. The multivariate logistic regression analysis revealed
that acute high-signal lesions on diffusion-weighted imaging (DWI), duration of
carbon monoxide (CO) exposure, and Glasgow Coma Scale (GCS) score were independent risk factors for
DEACMP (Odds Ratio = 6.230, 1.323, 0.714, p