Cervical Cancer Therapy and Prognosis

Dear Colleagues,

Globally, cervical cancer is the most commonly diagnosed gynecological cancer. With an estimated 570,000 cases and 311,000 deaths worldwide, cervical cancer is the fourth most commonly diagnosed cancer and the fourth leading cause of cancer-related death in women. Patients with locally advanced cervical cancer are primarily treated with concurrent cisplatin-based chemoradiotherapy. However, long-term progression-free survival and overall survival outcomes remain suboptimal, particularly for patients with larger tumors, lymph node metastases, and advanced disease.

In order to effectively treat cervical cancer, a multidisciplinary approach that includes surgery, radiotherapy, and systemic agents, is essential. Parallel to the innovations in treatment modalities, a rise in treatment efficacy and a decline in adverse events have been observed. In addition, radiotherapy increases the therapeutic efficacy of new systemic agents. Even in patients with recurrent or metastatic disease, the combined use of new generation systemic agents and new radiotherapy techniques is thought to improve survival.

This special edition will contain:
• A section describing the role of radiotherapy in the treatment of cervical cancer, as well as a section describing new treatment approaches;
• Original articles and (Systematic) Review articles with cervical cancer patients treated with radiotherapy, surgery, and/or systemic therapy; 
• A section on clinical perspectives, in which invited opinion leaders will provide their thoughts on the treatment of cervical cancer.

Prof. Dr. Cem Onal and Prof. Dr.  Guler Yavas
Guest Editors

Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 1500 USD. Submitted manuscripts should be well formatted in good English.